兔抗TBRG4多克隆抗体

Background:

TBRG4 (transforming growth factor beta regulator 4), also known as CPR2 (cell cycle progression restoration protein 2) or FASTKD4 (FAST kinase domain-containing protein 4), is a 631 amino acid protein that contains one RAP domain and belongs to the FAST kinase family. TBRG4 is ubiquitously expressed and may have a role in cell cycle progression. Existing as two alternatively spliced isoforms, the gene encoding TBRG4 maps to human chromosome 7p13. Chromosome 7 is approximately 158 million bases long, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Applications:

WB, IHC

Name of antibody:

TBRG4

Immunogen:

Fusion protein of human TBRG4

Full name:

transforming growth factor beta regulator 4

Synonyms：

TBRG4; CPR2; FASTKD4; KIAA0948

SwissProt:

Q969Z0

IHC positive control:

Human lymphoma

IHC Recommend dilution:

50-200

WB Predicted band size:

71 kDa

WB Positive control:

HeLa and HepG2 cells

WB Recommended dilution:

500-2000