兔抗ARL2BP多克隆抗体

Background:

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.

Applications:

ELISA, IHC

Name of antibody:

ARL2BP

Immunogen:

Fusion protein of human ARL2BP

Full name:

ADP ribosylation factor like GTPase 2 binding protein

Synonyms:

BART; RP66; BART1

SwissProt:

Q9Y2Y0

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human thyroid cancer

IHC Recommend dilution:

20-100