兔抗HUWE1多克隆抗体
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≥ 1支¥1800.00
中文名称: 兔抗HUWE1多克隆抗体
英文名称:Anti-HUWE1 rabbit polyclonal antibody
级 别: MULE; Ib772; LASU1; UREB1; HECTH9; URE-B1; ARF-BP1; HSPC272
抗 原: HUWE1
储 存: 冷冻(-20℃)
宿 主: Rabbit
相关类别:一抗
反应种属:Human, Mouse, Rat
标 记 物:Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation. |
Applications: | ELISA, IHC |
Name of antibody: | HUWE1 |
Immunogen: | Synthetic peptide of human HUWE1 |
Full name: | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
Synonyms: | MULE; Ib772; LASU1; UREB1; HECTH9; URE-B1; ARF-BP1; HSPC272 |
SwissProt: | Q7Z6Z7 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human esophagus cancer and human lung cancer |
IHC Recommend dilution: | 10-50 |