详情

Background:

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

Applications:

WB, IHC, IF

Name of antibody:

IRS1(Ab-312)

Immunogen:

Synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 312 (A-T-S(p)-P-A).

Full name:

insulin receptor substrate 1

Synonyms：

HIRS-1

SwissProt:

P35568

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

132 kDa

WB Positive control:

NIH/3T3 cells lysate

WB Recommended dilution:

500-3000

IF positive control:

Hela cells

IF Recommend dilution:

100-500