兔抗MKL1多克隆抗体

Background:

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.

Applications:

WB

Name of antibody:

MKL1

Immunogen:

Synthesized peptide derived from N-terminal of human MKL1.

Full name:

megakaryoblastic leukemia (translocation) 1

Synonyms：

MAL; BSAC; MRTF-A

SwissProt:

Q969V6

WB Predicted band size:

99 kDa

WB Positive control:

Hela cells and Huvec cells lysates

WB Recommended dilution:

500-3000