兔抗CDKL4多克隆抗体

Background:

Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation. Cdks are also involved in the regulation of transcription and mRNA processing. CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation.

Applications:

ELISA, WB, IHC

Name of antibody:

CDKL4

Immunogen:

Synthetic peptide of human CDKL4

Full name:

cyclin dependent kinase like 4

SwissProt:

Q5MAI5

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human ovarian cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

43 kDa

WB Positive control:

Human heart tissue lysate

WB Recommended dilution:

500-2000