兔抗H3-3B多克隆抗体

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded by this gene is a replication-independent histone that is a member of the histone H3 family. Pseudogenes of this gene have been identified on the X chromosome, and on chromosomes 5, 13 and 17. [provided by RefSeq, Oct 2015]

Applications:

ELISA, WB, IHC

Name of antibody:

H3-3B

Immunogen:

Fusion protein of human H3-3B

Full name:

H3.3 histone B

Synonyms:

H3.3B; H3F3B

SwissProt:

P84243

IHC positive control:

Human esophagus cancer and Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

15 kDa

WB Positive control:

LO2, A549 and 231 cell lysates

WB Recommended dilution:

200-1000