兔抗CCL11多克隆抗体

Background:

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Applications:

ELISA, IHC

Name of antibody:

CCL11

Immunogen:

Synthetic peptide of human CCL11

Full name:

C-C motif chemokine ligand 11

Synonyms:

SCYA11

SwissProt:

P51671

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer;

IHC Recommend dilution:

20-100