兔抗ACHE多克隆抗体

WB Predicted band size:

68 kDa

WB Positive control:

Raji cells

WB Recommended dilution:

200-1000

IHC Recommend dilution:

25-100

IHC positive control:

Human liver cancer and Human colon cancer

ELISA Recommended dilution:

1000-2000

SwissProt:

P22303

Synonyms：

YT; ACEE; ARACHE; N-ACHE

Full name:

acetylcholinesterase

Immunogen:

Synthetic peptide of human ACHE

Name of antibody:

ACHE

Applications:

ELISA, WB, IHC

Background:

Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.