兔抗MITF(Phospho-Ser18073)多克隆抗体

Background:

This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.

Applications:

WB

Name of antibody:

MITF(Phospho-Ser180/73)

Immunogen:

Peptide sequence around phosphorylation site of Serine 180(P-N-S(p)-P-M)/Serine 73(Q-E-R(p)-R-E) derived from Human MITF.

Full name:

microphthalmia-associated transcription factor

Synonyms：

MI; WS2; CMM8; WS2A; bHLHe32

SwissProt:

O75030

WB Predicted band size:

59 kDa

WB Positive control:

Mouse brain tissue lysates

WB Recommended dilution:

500-1000