兔抗ADSL多克隆抗体

Background:

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

ADSL

Immunogen:

Fusion protein of human ADSL

Full name:

adenylosuccinate lyase

Synonyms：

ASL; AMPS; ASASE

SwissProt:

P30566

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human breast cancer and Human lung cancer

IHC Recommend dilution:

15-50