兔抗DCLK1多克隆抗体

Background:

This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity.

Applications:

ELISA, IHC

Name of antibody:

DCLK1

Immunogen:

Synthetic peptide of human DCLK1

Full name:

doublecortin-like kinase 1

Synonyms:

CL1; DCLK; CLICK1; DCDC3A; DCAMKL1

SwissProt:

O15075

IHC positive control:

Human gastric cancer and human thyroid cancer

IHC Recommend dilution:

25-100