兔抗BTBD6多克隆抗体
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≥ 1支¥1800.00
中文名称: 兔抗BTBD6多克隆抗体
英文名称:Anti-BTBD6 rabbit polyclonal antibody
别 名: BDPL
相关类别:一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: BTBD6
反应种属:Human, Mouse
标 记 物:Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | BTBD6 (BTB/POZ domain-containing protein 6), also known as BDPL or lens BTB domain protein, is a 410 amino acid protein that contains one BTB/POZ domain and is specifically expressed in the lens. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD6 may play a role in transcription regulation in the lens. |
Applications: | ELISA, WB, IHC |
Name of antibody: | BTBD6 |
Immunogen: | Synthetic peptide of human BTBD6 |
Full name: | BTB domain containing 6 |
Synonyms: | BDPL |
SwissProt: | Q96KE9 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human esophagus cancer |
IHC Recommend dilution: | 10-50 |
WB Predicted band size: | 53 kDa |
WB Positive control: | Human gastric carcinoma tissue lysate |
WB Recommended dilution: | 200-1000 |