兔抗ATF2(Phospho-Thr71or53)多克隆抗体

Background:

Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.

Applications:

WB, IHC

Name of antibody:

ATF2 (Phospho-Thr71 or 53)

Immunogen:

Synthetic peptide of human ATF2 (Phospho-Thr71 or 53)

Full name:

activating transcription factor 2 (Phospho-Thr71 or 53)

Synonyms：

HB16; CREB2; TREB7; CRE-BP1

SwissProt:

P15336

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

65-75 kDa

WB Positive control:

HUVEC cells treated with Anisomycin

WB Recommended dilution:

500-1000