兔抗EIF2S2(Ab-67)多克隆抗体

Background:

eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Applications:

WB

Name of antibody:

EIF2S2(Ab-67)

Immunogen:

Synthesized peptide derived from N-terminal of human eIF2B.

Full name:

eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa

Synonyms：

EIF2; EIF2B; PPP1R67; EIF2beta; eIF-2-beta

SwissProt:

P20042

WB Predicted band size:

38 kDa

WB Positive control:

K562 cells lysate

WB Recommended dilution:

500-3000