兔抗CREB1(Ab-129133)多克隆抗体

Background:

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Applications:

WB, IHC

Name of antibody:

CREB1(Ab-129/133)

Immunogen:

Synthesized non-phosphopeptide derived from human CREB around the phosphorylation site of serine 129 or serine 133(S-R-R-P-S).

Full name:

cAMP responsive element binding protein 1

Synonyms：

CREB

SwissProt:

P16220

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

37 kDa

WB Positive control:

Hela cells treated with UV lysate

WB Recommended dilution:

500-3000