详情

Background:

This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

ITPA

Immunogen:

Full length fusion protein

Full name:

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

Synonyms：

My049; C20orf37; dJ794I6.3; HLC14-06-P

SwissProt:

Q9BY32

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human brain and Human liver cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

21 kDa

WB Positive control:

Human fetal liver tissue and Hela cells

WB Recommended dilution:

200-1000