兔抗TAX1BP1多克隆抗体

Background:

This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[

Applications:

ELISA, IHC

Name of antibody:

TAX1BP1

Immunogen:

Fusion protein of human TAX1BP1

Full name:

Tax1 (human T-cell leukemia virus type I) binding protein 1

Synonyms：

T6BP; TXBP151; CALCOCO3

SwissProt:

Q86VP1

ELISA Recommended dilution:

3000-10000

IHC positive control:

Human colon cancer and human esophagus cancer

IHC Recommend dilution:

100-300