兔抗MIDN多克隆抗体

Background:

Expression of the midnolin gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. The midnolin encodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain. The intracellular distribution of the midnolin was studied by using midnolin-green fluorescent protein (GFP) fusion proteins. Midnolin was found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the midnolin. May be involved in regulation of genes related to neurogenesis in the nucleolus

Applications:

ELISA, WB

Name of antibody:

MIDN

Immunogen:

Synthetic peptide of human MIDN

Full name:

Midnolin

SwissProt:

Q504T8

ELISA Recommended dilution:

1000-5000

WB Predicted band size:

49 kDa

WB Positive control:

Human lung tissue

WB Recommended dilution:

500-2000