兔抗GEMIN2多克隆抗体

Background:

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Applications:

ELISA, WB, IHC

Name of antibody:

GEMIN2

Immunogen:

Synthetic peptide of human GEMIN2

Full name:

gem (nuclear organelle) associated protein 2

Synonyms：

SIP1, SIP1-delta

SwissProt:

O14893

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human ovarian cancer and Human breast cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

32 kDa

WB Positive control:

K562 and hela cells

WB Recommended dilution:

200-1000