兔抗CD207多克隆抗体

Background:

The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.

Applications:

ELISA, WB, IHC

Name of antibody:

CD207

Immunogen:

Fusion protein of human CD207

Full name:

CD207 molecule

Synonyms:

CLEC4K

SwissProt:

Q9UJ71

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

250-500

WB Predicted band size:

37 kDa

WB Positive control:

Mouse skin tissue lysate

WB Recommended dilution:

500-2000