详情

Background:

The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Applications:

ELISA, IHC

Name of antibody:

MAD2L1BP

Immunogen:

Fusion protein of human MAD2L1BP

Full name:

MAD2L1 binding protein

Synonyms：

CMT2; RP1-261G23.6

SwissProt:

Q15013

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human colon cancer and human lung cancer

IHC Recommend dilution:

100-300