兔抗DSC1多克隆抗体

Background:

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.

Applications:

ELISA, IHC

Name of antibody:

DSC1

Immunogen:

Synthetic peptide of human DSC1

Full name:

desmocollin 1

Synonyms:

CDHF1; DG2/DG3

SwissProt:

Q08554

IHC positive control:

Human gastric cancer and human brain

IHC Recommend dilution:

50-200