详情

Background:

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

VPS16

Immunogen:

Fusion protein of human VPS16

Full name:

VPS16 core subunit of CORVET and HOPS complexes

Synonyms:

hVPS16

SwissProt:

Q9H269

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100