兔抗DHFR多克隆抗体

Background:

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

DHFR

Immunogen:

Fusion protein of human DHFR

Full name:

dihydrofolate reductase

Synonyms:

DYR; DHFRP1

SwissProt:

P00374

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

50-300