详情

Background:

This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for malonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent malonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found.

Applications:

ELISA, WB, IHC

Name of antibody:

MMAB

Immunogen:

Fusion protein of human MMAB

Full name:

malonic aciduria (cobalamin deficiency) cblB type

Synonyms:

ATR; cob; cblB; CFAP23

SwissProt:

Q96EY8

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

27 kDa

WB Positive control:

MCF-7, 293T, LO2 and HepG2 cell lysates

WB Recommended dilution:

1000-5000