详情

Background:

This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.

Applications:

ELISA, IHC

Name of antibody:

ALOX15B

Immunogen:

Fusion protein of human ALOX15B

Full name:

arachidonate 15-lipoxygenase, type B

Synonyms：

15-LOX-2

SwissProt:

O15296

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

15-50