兔抗MBP多克隆抗体
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中文名称: 兔抗MBP多克隆抗体
英文名称:Anti-MBP rabbit polyclonal antibody
别 名: MGC99675
相关类别:一抗
储 存: 冷冻(-20℃) 避光
宿 主: Rabbit
抗 原: MBP
反应种属:Human, Mouse, Rat
标 记 物:Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation. |
Applications: | WB |
Name of antibody: | MBP |
Immunogen: | Synthetic peptide of human MBP |
Full name: | myelin basic protein |
Synonyms: | MGC99675 |
SwissProt: | P02686 |
WB Predicted band size: | 33 kDa |
WB Positive control: | Rat brain, Mouse brain and Rat hippocampus Tissue |
WB Recommended dilution: | 500-1000 |