详情

Background:

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.

Applications:

ELISA, WB, IHC

Name of antibody:

TDP2

Immunogen:

Synthetic peptide of human TDP2

Full name:

tyrosyl-DNA phosphodiesterase 2

Synonyms:

EAP2; AD022; EAPII; TTRAP; hTDP2; dJ30M3.3

SwissProt:

O95551

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer and Human thyroid cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

41 kDa

WB Positive control:

Mouse small intestines tissue lysate

WB Recommended dilution:

500-2000