兔抗ABCD1多克隆抗体

Background:

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Applications:

ELISA, IHC

Name of antibody:

ABCD1

Immunogen:

Synthetic peptide of human ABCD1

Full name:

ATP binding cassette subfamily D member 1

Synonyms:

ALD; AMN; ALDP; ABC42

SwissProt:

P33897

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and human tonsil

IHC Recommend dilution:

60-450