兔抗CSF1R多克隆抗体

Background:

The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.

Applications:

ELISA, WB

Name of antibody:

CSF1R

Immunogen:

Synthetic peptide of human CSF1R

Full name:

Colony stimulating factor 1 receptor

Synonyms：

FMS, CSFR, FIM2, HDLS, C-FMS, CD115, CSF-1R, M-CSF-R

SwissProt:

P07333

ELISA Recommended dilution:

1000-5000

WB Predicted band size:

108 kDa

WB Positive control:

231 cells

WB Recommended dilution:

500-2000