详情

Background:

This gene encodes a molecular chaperone that is a member of the chaperonin-containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

CCT6B

Immunogen:

Fusion protein of human CCT6B

Full name:

chaperonin containing TCP1 subunit 6B

Synonyms:

Cctz2; CCTZ-2; TSA303; CCT-zeta-2; TCP-1-zeta-2

SwissProt:

Q92526

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

40-200

WB Predicted band size:

58 kDa

WB Positive control:

293T cell lysate

WB Recommended dilution:

200-1000