兔抗HDAC8多克隆抗体

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors.

Applications:

ELISA, IHC

Name of antibody:

HDAC8

Immunogen:

Fusion protein of human HDAC8

Full name:

histone deacetylase 8

Synonyms：

HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1

SwissProt:

Q9BY41

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain and human esophagus cancer

IHC Recommend dilution:

50-200