小鼠抗TNFRSF8单克隆抗体

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Applications:

WB

Name of antibody:

TNFRSF8

Immunogen:

Fusion protein of human TNFRSF8

Full name:

TNF receptor superfamily member 8

Synonyms:

CD30; Ki-1; D1S166E

SwissProt:

P28908

WB Predicted band size:

64 KD

WB Positive control:

A431, Hela cell lysates

WB Recommended dilution:

500-2000