兔抗AD7C-NTP多克隆抗体

Background:

The predicted AD7CNTP protein contains 375 amino acids and has a calculate molecular mass of about 42 kD. It is rich in serine and proline residues, has a 15-amino acid hydrophobic leader sequence, and has 7 putative membrane-spanning regions. AD7CNTP has several phosphorylation sites, a myristoylation site, and 2 serine/threonine kinase protein domains. Northern blot analysis detected 1.4- and 0.9-kb transcripts only in adult frontal and temporal lobe. In vitro studies demonstrated that overexpression of AD7CNTP in transfected neuronal cells promoted neuritic sprouting and cell death, the 2 principal neuroanatomic lesions correlated with dementia in AD.

Applications:

ELISA, WB, IHC

Name of antibody:

AD7C-NTP

Immunogen:

Synthetic peptide of human AD7C-NTP

Full name:

Neuronal thread protein AD7c-NTP

Synonyms：

AD7CNTP

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100

WB Predicted band size:

41 kDa

WB Positive control:

Human fetal brain tissue

WB Recommended dilution:

200-1000