兔抗DPYSL2(Phospho-Thr509)多克隆抗体

Background:

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Applications:

WB, IHC

Name of antibody:

DPYSL2(Phospho-Thr509)

Immunogen:

Peptide sequence around phosphorylation site of threonine 509 (S-V-T(p)-P-K) derived from Human CRMP-2.

Full name:

dihydropyrimidinase-like 2

Synonyms：

DRP2; N2A3; CRMP2; DRP-2; ULIP2; CRMP-2; DHPRP2; ULIP-2

SwissProt:

Q16555

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

62 kDa

WB Positive control:

HT29 cells lysates treated with heat shock

WB Recommended dilution:

500-1000