兔抗MAPK8多克隆抗体
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≥ 1支¥1800.00
中文名称:兔抗MAPK8多克隆抗体
英文名称:Anti-MAPK8 rabbit polyclonal antibody
别 名: JNK, JNK1, PRKM8, SAPK1, JNK-46, JNK1A2, SAPK1c, JNK21B1/2
抗 原: MAPK8
储 存: 冷冻(-20℃)
宿 主: Rabbit
相关类别:一抗
反应种属:Human, Mouse, Rat
标记物: Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Applications: | ELISA, WB, IHC |
Name of antibody: | MAPK8 |
Immunogen: | Fusion protein of human MAPK8 |
Full name: | mitogen-activated protein kinase 8 |
Synonyms: | JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2 |
SwissProt: | P45983 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human prostate cancer and Human liver cancer |
IHC Recommend dilution: | 50-200 |
WB Predicted band size: | 48 kDa |
WB Positive control: | Jurkat, K562, Hela, A172 cell, Mouse brain tissue lysates |
WB Recommended dilution: | 500-2000 |