兔抗CBS多克隆抗体

Background:

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

CBS

Immunogen:

Fusion protein of human CBS

Full name:

cystathionine-beta-synthase

Synonyms：

HIP4

SwissProt:

P35520

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

61 kDa

WB Positive control:

Mouse pancreas and human fetal liver tissue

WB Recommended dilution:

200-1000