详情

Background:

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

FCGR2B(Phospho-Tyr292)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32.

Full name:

Fc fragment of IgG, low affinity IIb, receptor (CD32)

Synonyms：

CD32; FCG2; CD32B; FCGR2; IGFR2

SwissProt:

P31994

WB Predicted band size:

34 kDa

WB Positive control:

K562 cells lysates treated with PMA

WB Recommended dilution:

500-1000