兔抗GRIN1(Phospho-Ser890)多克隆抗体

Background:

The protein encoded by this gene is a critical subunit of N--D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

Applications:

IHC, IF

Name of antibody:

GRIN1(Phospho-Ser890)

Immunogen:

Peptide sequence around phosphorylation site of Serine 890(A-S-S(p)-F-K) derived from Human NMDAR1.

Full name:

glutamate receptor, ionotropic, N- D-aspartate 1

Synonyms：

NR1; MRD8; GluN1; NMDA1; NMDAR1

SwissProt:

Q05586

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

IF positive control:

A549 cells

IF Recommend dilution:

100-200