详情

Background:

High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

Applications:

ELISA, WB

Name of antibody:

SLAMF1

Immunogen:

Fusion protein of human SLAMF1

Full name:

signaling lymphocytic activation molecule family member 1

Synonyms：

SLAM; CD150; CDw150

SwissProt:

Q13291

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

37 kDa

WB Positive control:

Jurkat cells

WB Recommended dilution:

200-1000